| Objective: To observe the effect of modified eight-style sitting Tai Chi on the health-related quality of life in patients with lung cancer during chemotherapy. Methods: Totally, 59 patients were divided into treatment group (29 cases) and control group (30 cases) in a prospective controlled trial. The control group received routine treatment in chemotherapy department, and the treatment group received eight-style sitting Tai Chi training once a day, 20-30 min, guided by the therapist on basis of routine treatment. Before, and 6 weeks and 12 weeks after treatment, the patients in the two groups were evaluated with the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire core 30/lung cancer 13 (EORTC QLQ-C30/LC13). Results: After 6 weeks of treatment, the scores of overall health level, role function, emotional function and cognitive function in the treatment group were significantly higher than those before treatment (all P<0.05), while the scores of fatigue, nausea and vomiting, dyspnea, dyspnea(LC13), numbness of hands and feet and pain in chest were significantly lower than those before treatment (all P<0.05). After 12 weeks of treatment, the scores of overall health, physical function, role function, emotional function and cognitive function in the treatment group were significantly higher than those before treatment (all P<0.05), while the scores of fatigue, nausea and vomiting, dyspnea, dyspnea(LC13), cough, numbness of hands and feet and pain in chest were significantly lower than those before treatment (all P<0.05). After 6 weeks of treatment, the dyspnea(LC13) score in the control group was significantly lower than that before treatment (P<0.05). After 12 weeks of treatment, the scores of cognitive function in the control group were significantly higher than those before treatment (P<0.05), while the scores of dyspnea(LC13), numbness of hands and feet and pain in chest were significantly lower than those before treatment (all P<0.05). After 6 weeks of treatment, the overall health level and role function scores in the treatment group were significantly higher than those in the control group (all P<0.05), while the scores of fatigue and dyspnea were significantly lower than those in the control group (all P<0.05). After 12 weeks of treatment, the scores of fatigue and dyspnea in the treatment group were significantly lower than those in the control group (all P<0.05). Conclusion: The modified eight-style sitting Tai Chi training under supervision during chemotherapy is safe and beneficial for patients with lung cancer. It can help improve health-related quality of life in lung cancer patients during chemotherapy. However, the follow-up period of this study is short, and in-depth clinical studies on long-term functional indicators need to be conducted in the future. |
