| Objective：To observe the effects of low-frequency repetitive transcranial magnetic stimulation (rTMS) on post-stroke cognitive impairment (PSCI) and lipid metabolism. Methods: Forty-three PSCI patients were randomly divided into rTMS group (n=21) and Sham rTMS group (n=22). Both groups were given conventional rehabilitation therapy. The rTMS group was given the contralateral dorsolateral prefrontal cortex (DLPFC) 1Hz, 90% motor threshold rTMS treatment, and the Sham group was given false stimulation for 4 weeks. Before and 4 weeks after treatment, the patient’s cognitive function was assessed with the Mini Mental State Scale (MMSE) and Montreal Cognitive Scale (MoCA), and the patient’s thyroid hormone and blood lipid levels were measured. Results: After treatment, the MMSE score and MoCA score in the two groups were significantly higher than those before treatment (P<0.05), and the MMSE score and MoCA score in the rTMS group were significantly higher than those in the Sham group (P<0.05). After treatment in the rTMS group, serum triiodothyronine (T3) and thyroid-stimulating hormone (TSH) levels were significantly higher than those before treatment (P<0.05); total cholesterol (TCHO) levels were significantly lower than those before treatment (P<0.05). Conclusion: Low-frequency rTMS can improve the cognitive function of PSCI patients, and can increase serum T3 and TSH levels, while reducing TCHO levels. |
