| Objective: To provide evidence-based basis for hemiplegic shoulder pain (HSP) rehabilitation and evaluate the efficacy of steroids injection for HSP treatment. Methods: An extensive search of related literature from Web of Science, EMBASE, The Cochrane Library, PubMed, CNKI, Wanfang, VIP database was performed from the inception to July 2020. The randomized controlled trails (RCTs) comparing the effects of steroids injection in sub-acromial or intra-articular shoulder with blank/placebo were collected. Two reviewers independently screened literature, extracted data and assessed the risk of bias of included studies, then meta-analysis was performed by using RevMan 5.3 software and StataSE12.0. Results: Totally, 9 RCTs including 416 cases were finally included with 5 English articles and 4 Chinese articles. As compared with blank/placebo group, HSP patients’ pain was significantly reduced ［SMD＝0.93, 95%CI (0.71, 1.14), Z=8.46, P<0.01］, activities of daily living ［SMD=-0.42, 95%CI (-0.65, -0.20), Z=3.71, P=0.0002］ and functional level of upper extremity significantly improved ［SMD＝-1.02，95%CI（-1.68，-0.36），Z＝3.02，P＝0.003］, and shoulder flexion ［MD＝-15.41, 95%CI (-23.30, -7.52), Z=3.83, P=0.0001］, abduction ［MD=-12.16, 95%CI (-15.67, -8.65), Z=6.79, P<0.01］, external rotation ［MD＝-8.47, 95%CI (-9.94, -7.00), Z=11.30, P<0.01］ and internal rotation ［MD=-2.95, 95%CI (-4.57, -1.32), Z=3.56, P=0.0004］significantly increased in steroids injection group. Conclusion: Steroids injection can safely and effectively reduce the pain of HSP patients and promote the upper limb rehabilitation. |
