| Objective: To explore the effect of progressive resistance inspiratory muscle training on respiratory mechanics, pulmonary function and dyspnea (mMRC) classification in stroke patients with chronic obstructive pulmonary disease (COPD). Methods: A total of 114 stroke patients with COPD were randomly divided into treatment group and control group with 57 cases each. The control group was given regular breathing training, and the treatment group was subjected to progressive resistance inspiratory muscle training based on the control group for a total of 6 weeks. The number of acute exacerbations, the number of hospitalizations and the respiratory mechanics indexes ［resonance frequency (Fres), respiratory resistance at 5 Hz (R5), compliance (Cl), airway resistance (Raw)］, pulmonary function ［forced expiratory vohime in the first second (FEV1%), forced expiratory volume in the first s/forced vital capacity (FEV1/FVC), forced vital capacity (FVC)］, 6-min walking distance (6MWD), diaphragm function ［diaphragmatic thickness at the end of inspiration (DTei), diaphragmatic thickness at the end of expiration (DTee), diaphragm movement］, mMRC grade, severity of illness (CAT), quality of life (SGRQ) before and after treatment were measured. Results: The number of acute exacerbations and hospitalizations in the treatment group were less than those in the control group (both P<0.05). After 6 weeks of treatment, the Fres, R5 and Raw in the treatment group were lower than those of the control group, and Cl was higher than the control group (all P<0.05). The FEV1/FVC, FVC, FEV1% and 6MWD in the treatment group were higher than those in the control group (all P＜0.05), the diaphragmatic mobility and DTei of the treatment group were greater than those of the control group (both P<0.05). The scores of mMRC, CAT and SGRQ of the treatment group were lower than those of the control group (all P＜0.05), and the comparison between the treatment group and the control group at the same time point, except for DTee, revealed all other indicators were statistically significant. Conclusion: Progressive resistance inspiratory muscle training can improve the respiratory mechanics of stroke patients with COPD, restore diaphragm function and pulmonary function, and play an important role in relieving breathing difficulties, reducing the severity of the disease, and improving the quality of life. |
