| Objective:To study the effects of high-intensity interval aerobic training（HIIT） on body mass index (BMI)，biochemical indexes, cardiopulmonary function and quality of life in type 2 diabetic patients under the guidance of cardiopulmonary exercise test (CME).Methods： A total of 90 patients with type 2 diabetes were randomly divided into three groups: HIIT group, CME group and control group.All enrolled patients were evaluated at baseline prior to the start of the trial.Control group received routine diabetic diet, exercise education and standard drug treatment; HIIT group was given HIIT, 5 days a week for 12 weeks,based on the control group;CME group was subjected go continuous moderate-intensity aerobic training，5 days a week for 12 weeks，in addition to the control group.BMI, biochemical indexes, cardiopulmonary function, quality of life and other indicators of the patients were evaluated again after the trial. Results： Before treatment, there were no significant differences in BMI，biochemical indexes, cardiopulmonary endurance and quality of life indexes among 3 groups. There were no significant differences in the indicators in the control group before and after treatment. After 12 weeks of treatment, all other indexes in HIIT group except TG and CME group except TC were significantly improved compared with those before treatment (all P<0.05). After 12 weeks of treatment, BMI, FBG, HbA1c, FINS, HOMA-IR, TG, VO2peak, AT, METS, total score of DSQL, physiological dimension, psychological dimension and mental dimension in HIIT group were significantly better than those in the control group(all P<0.05). HbA1c in HIIT group was significantly improved compared with those in CME group(P < 0.05). Conclusion: HIIT can improve the blood glucose level, insulin resistance, cardiopulmonary function and quality of life in diabetic patients, and the safety of individual aero-bic training of exercise intensity can be further guaranteed under the guidance of CME, and it is worthy of promotion in clinical treatment. |
