| Objective： To explore the characteristics of cardiopulmonary exercise test in heart failure patients with different ejection fractions. Methods： A total of 438 patients with heart failure who underwent cardiopulmonary exercise test in Tongji Hospital Heart Rehabilitation Center Affiliated to Tongji University from March 2007 to July 2019 were collected retrospectively, and the characteristics of cardiopulmonary exercise test in heart failure patients with different ejection fractions were compared, including 153 patients with heart failure with reduced ejection fraction (HFrEF), 115 patients with heart failure with mid-range ejection fraction (HFmrEF) and 170 patients with heart failure with preserved ejection fraction (HFpEF). Results： Because there were statistically significant differences in some baseline data among the three groups (the age was older and female ratio was higher in HFpEF group than those in the rest two groups,（all P<0.05), the comparison between the subgroups was made after matching the propensity score. The results showed that there were significant differences in peak circulatory power (CPpeak), peak oxygen pulse (peak VO2/HR), load peak, the slope of minute ventilation versus carbon dioxide production (VE/VCO2 slope) (all P<0.01), peak oxygen consumption (VO2 peak) and load power at anaerobic threshold (load AT) (all P<0.05). Conclusions： There are significant differences in exercise endurance, pulmonary ventilation efficiency and peak circulatory power among heart failure patients with different ejection fractions, which may have some implications for the relationship between different phenotypes of heart failure. |
