Objective: To study the therapeutic effects of ultrasound-guided acupotomy combined with platelet-rich plasma (PRP) on knee osteoarthritis (KOA). Methods: A total of 72 patients with KOA were divided into observation group (36 cases) and control group (36 cases). Patients in the observation group received treatment of ultrasound-guided acupotomy combined with PRP, and those in the control group received intra articular injection of sodium hyaluronate and local blocking. The effects of the two groups were evaluated with effective rate, visual analogue score (VAS), Lysholm knee score and absolute symmetry index (ASI). Results: After 3 months, the markedly effective rate in the observation group and control group was 86.11% and 27.78% respectively, and the difference was significant (P<0.01). Meanwhile, VAS (2.50±0.34 vs. 4.05±0.39) and Lysholm knee score (85.03±3.25 vs. 79.28±3.42) in the observation group were better than those in the control group (all P<0.01). There were significant differences in the ASIs between the observation group and control group [stride frequency: (2.04±0.34 vs. 4.24±0.46); pace: (4.09±0.62 vs. 7.64±1.18); stride length: (4.67±0.41 vs. 6.36±0.57); and knee flexion angle: (5.21±1.06 vs. 7.38±1.19) (all P<0.05)]. Conclusion: Ultrasound-guided acupotomy combined with PRP injection can not only achieve the visualization and precision of acupotomy and PRP injection, but also realize the comprehensive intervention inside and outside the joint, and it can eventually improve the mobility of knee joint and walking stability of patients with KOA. |