Abstract
Application of hyperbaric oxygen in pneumoconiosis patients with different degrees of abnormal pulmonary function
  
DOI:
EN KeyWords: Pneumoconiosis  Lung function  Hyperbaric oxygen  Blood gas analysis
Fund Project:广西壮族自治区卫生和计划生育委员会自筹经费科研课题(Z2015025)
作者单位
石雅馨 广西职业病防治研究院高压氧科南宁530021 
卢世玲 广西职业病防治研究院高压氧科南宁530021 
王瑜 广西职业病防治研究院高压氧科南宁530021 
许婷 广西职业病防治研究院高压氧科南宁530021 
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EN Abstract:
  Objective: To study the application of hyperbaric oxygen in pneumoconiosis patients with different degrees of abnormal pulmonary function. Methods: A total of 160 cases of pneumoconiosis admitted to Guangxi Institute of Occupational Disease Prevention and Control from January 2019 to March 2021 were selected. According to the method of random number table, the patients were divided into the observation group and the control group, with 80 cases in each group. The patients in the control group received conventional treatment, and those in the observation group were treated with hyperbaric oxygen on the basis of the control group. Both groups were treated for 20 days. The changes in Borg scale scores, forced expiratory volume in the first second (FEV1), FEV1/forced vital capacity (FVC), and maximum ventilation per minute ( MVV), arterial blood oxygen saturation (SPO2), arterial blood oxygen partial pressure (PaO2) and arterial carbon dioxide partial pressure (PaCO2) were compared before and 20 days after treatment in two groups with different degrees of abnormal pulmonary function. Results: After 20 days of treatment, the Borg scale scores of patients with different degrees of pulmonary dysfunction in the two groups were significantly lower than those before treatment. The Borg scale scores of the patients in the mild, moderate, and severe subgroups in the observation group were significantly lower than those in the mild, moderate, and severe subgroups in the control group with the difference being statistically significant (P<0.05) After treatment, the FEV1, FEV1/FVC and MVV of patients with different degrees of pulmonary dysfunction in the two groups were significantly higher than those before treatment, and those of patients in the mild, moderate, and severe subgroups in the observation group were significantly higher than those in the mild, moderate, and severe subgroups in the control group with the difference being statistically significant (P<0.05). After treatment, the SPO2 and PaO2 of patients with different degrees of pulmonary dysfunction in the two groups were significantly higher than those before treatment, and PaCO2 was significantly lower than that before treatment. The SPO2 and PaO2 of patients in the mild, moderate, and severe subgroups in the observation group were significantly higher, and PaCO2 was significantly lower than those in the mild, moderate, and severe subgroups in the control group with the difference being statistically significant (P<0.05). Conclusi-on: Hyperbaric oxygen has obvious effectiveness in patients with pneumoconiosis with different degree of abnormal lung function, which is worthy of clinical promotion.
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