Objective: To study the efficacy of early family rehabilitation for motor and cognitive development in infant at high risk of cerebral palsy (IHRCP). Methods: A total of 115 infants at high risk of cerebral palsy were randomly divided into intervention group (n=57) and control group (n=58). Both groups were treated with early comprehensive intervention for 6 months in high-risk infants with cerebral palsy, and the intervention group was additionally given outpatient early family rehabilitation guidance and family rehabilitation. Before and 3 and 6 months after the intervention, the curative effectiveness was evaluated by gross motor function test scale (GMFM), fine motor function assessment scale (FMFM) and Gesell developmental diagnosis scale (GDDS). The infants were followed up at 12th month after correcting the gestational age, and the number of children diagnosed with global developmental delay (GDD), cerebral palsy (CP), autism spectrum disorder (ASD)/infant at high risk of autism spectrum disorder (IHRASD) were determined. Results: At 3rd and 6th month after intervention, the scores of GMFM, FMFM, adaptive behavior and language in the two groups were significantly increased as compared with those before treatment (P<0.05), and those in the intervention group were significantly higher than those in the control group (P<0.01). At 12th month after correcting gestational age, the number of patients diagnosed with GDD, CP, ASD/IHRASD in the intervention group was significantly less than that in the control group (P<0.05). Conclusion: Early family rehabilitation can improve gross motor function, fine motor function, cognitive and language function, and improve the poor prognosis of IHRCP. |