| Clinical study on different time sequence repetitive transcranial magnetic stimulation combined with routine swallowing therapy for dysphagia in ischemic stroke |
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| DOI： |
| EN KeyWords: repetitive transcranial magnetic stimulation stroke dysphagia |
| Fund Project:江苏省高层次卫生人才“六个一工程”拔尖人才项目（LGY2020030） |
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| EN Abstract: |
| Objective: To observe the effectiveness of different time sequence repetitive transcranial magnetic stimulation (rTMS) combined with routine swallowing therapy in the rehabilitation of patients with dysphagia after ischemic stroke. Methods: Totally, 60 patients with dysphagia after ischemic stroke who were hospitalized in our hospital from October 2020 to October 2021 were randomly divided into three groups: routine group, rTMS-routine timing group and routine-rTMS timing group. There were 20 cases in each group. Each group received routine rehabilitation training. The rTMS-routine timing group was given rTMS followed by routine rehabilitation training. The routine-rTMS timing group was subjected to routine rehabilitation training followed by rTMS. The frequency of rTMS was 10Hz, stimulation intensity was 80% RMT, stimulation time was 2 s, interval was 10 s, treatment time was 10 min. All the three groups were treated once a day, 5 days a week for 4 weeks. Before and after treatment, we evaluated the effectiveness by Wa Tian drinking water test, standardized swallowing assessment (SSA) and surface electromyography (sEMG). Results: After 4 weeks of treatment, the grading of Wa Tian drinking water test in the 3 groups was reduced as compared with that before treatment (P<0.05). The scores in rTMS-routine timing group and the routine-rTMS timing group were significantly lower than those in routine group (P<0.05), and those in rTMS-routine timing group was significantly lower than in routine-rTMS timing group (P<0.05). The SSA score in all groups after treatment was lower than before (P<0.05), and the RMS value was higher than before (P<0.05). rTMS-routine timing group and routine-rTMS timing group had significantly lower SSA scores (P<0.05) and higher RMS values than the routine group (P<0.05). As compared with routine-rTMS timing group, the RMS value in rTMS-routine timing group increased significantly (P<0.05), but there was no significant difference in SSA score. Conclusion: rTMS combined with routine treatment is more effective than routine treatment alone in improving dys-phagia after stroke, and the treatment plan of rTMS-routine timing series is the best. |
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