| Objective: To study the effect of transcranial direct current stimulation (tDCS) on attention function in patients with cognitive impairment after stroke and its possible mechanism. Methods: A total of 60 patients with attention impairment after stroke in the Department of Rehabilitation Department, Xuzhou Central Hospital from October 2021 to June 2022 were randomly divided into an experimental group and a control group (n=30 each). Both groups were treated with routine cognitive rehabilitation training. Additionally, the experimental group was given tDCS 5 times a week, 20 min each time for 4 weeks, and the control group was given electric current at the initiation and last 30 s. The attention span and persistence of patients were evaluated by digit span test (DST) and Alphabet Deletion Test, and the ability of attention transfer was evaluated by symbolic number pattern test (SDMT). The cognitive function and activities of daily living were evaluated by Montreal Cognitive Assessment scale (MoCA) and modified Barthel Index (MBI). At the same time, the improvement of latency and amplitude of event-related potential P300 in two groups were evaluated. Results: After treatment, the scores of MoCA, MBI, SDMT, DST, correct deletion, P300 latency and amplitude in the two groups were better than those before treatment (P<0.05), and the scores of MoCA, MBI, SDMT, DST, correct deletion, P300 latency and amplitude in the experimental group were higher than those in the control group after treatment (all P<0.05). Conclusion: tDCS therapy on the basis of routine treatment can improve patients’ attention function and improve the level of cognition and activities of daily living. |
