Abstract
Application of functional near-infrared spectroscopy in effectiveness evaluation of upper limb exergames in the treatment of stroke patients with mild cognitive impairment
  
DOI:
EN KeyWords: functional near-infrared spectroscopy  stroke  upper limb exergames  cognitive function assessment
Fund Project:中央级公益性科研院所基本科研业务费专项资金(2019CZ-11);中国康复研究中心课题(2021zx-Q4)
作者单位
李秀丽 1.中国康复研究中心北京博爱医院作业疗法科北京 1000682.首都医科大学康复医学院北京 100068 
李珊 1.中国康复研究中心北京博爱医院作业疗法科北京 1000682.首都医科大学康复医学院北京 100068 
冯梦晨 1.中国康复研究中心北京博爱医院作业疗法科北京 1000682.首都医科大学康复医学院北京 100068 
黄富表 1.中国康复研究中心北京博爱医院作业疗法科北京 1000682.首都医科大学康复医学院北京 100068 
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EN Abstract:
  Objective: To explore the therapeutic effect of upper limb exergames on stroke patients with mild cognitive impairment and the application of functional near-infrared spectroscopy(fNIRS) in cognitive efficacy evaluation of stroke patients. Methods: A total of 46 stroke patients with mild cognitive impairment were divided into observation group and control group according to the random number table method, 23 cases in each group. The control group was treated with upper limb functional motor training, 30 min/time, 1 time/day, 5 days/week, a total of 4 weeks. The observation group received upper limb exergames, 30 min/time, 1 time/day, 5 days/week, a total of 4 weeks. Before and after treatment, Montreal cognitive assessment(MoCA), fNIRS, Fugl-Meyer assessment-Upper Limb(FMA-UL) and modified Barthel index(MBI) were used to evaluate the treatment effectiveness of patients. Results: After treatment, the scores of fNIRS centroid values, cognition, motor and activities of daily living in the control group and the observation group were improved as compared with those before treatment (P<0.05). The improvement of cognitive function, fNIRS centroid values and motor function in the observation group was more significant than the control group (P<0.05). There was no significant difference in activity of daily living between the two groups. Increased MoCA scores in stroke patients with mild cognitive impairment were positively correlated with decreased fNIRS centroid values ( P<0.01). Conclusion: Upper limb exergames training can better improve mild cognitive impairment and motor dysfunction after stroke. Functional near infrared spectroscopy technology can be applied to evaluate the therapeutic effectiveness of rehabilitation of cognitive dysfunction after stroke.
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