| Objective: To investigate the efficacy of high- and low-frequency repeated transcranial magnetic stimulation (rTMS) in patients with post-stroke cognitive impairment and feeding dysphagia. Methods: A total of 60 stroke patients hospitalized in the Rehabilitation Medicine Department of Xuzhou Central Hospital evaluated as cognitive impairment and swallowing graphy (VFSS) were randomly divided into control group and observation group, 30 patients in each group. All the patients were given basic drug therapy, routine swallowing rehabilitation training, and routine cognitive function training. On this basis, the observation group was sabjected to high- and low-frequency rTMS, and the control group received high- and low-frequency rTMS pseudostimulation. After 3 weeks of treatment, all patients were evaluated for the cerebral neurotrophic index, cerebral hemodynamics index, MMSE scale, and swallowing function, respectively. Results: The levels of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) were increased after the treatment (P<0.05), and those in the observation group were lower than those in the control group (P<0.05). The maximum peak flow velocity (MPV) and mean flow velocity (Vm) after treatment were faster (P<0.05), and vascular resistance index (RI) was lower (P<0.05) than those before treatment. MPV and Vm in the observation group were faster than those in the control group (P<0.05). The RI was lower in the observation group than that in the control group (P<0.05). MMSE scale scores in both groups after treatment were increased (P<0.05), and those in the observation group were higher than in the control group (P<0.05). The dysphagia scale (VDS) score decreased after treatment in both groups(P<0.05), and the score in the observation group was significantly lower than in the control group (P<0.05). Oral delivery time (OTT) and soft jaw braces time (SET) after treatment in both groups were shortened (P<0.05), and those in the observation group were significantly shorter than in the control group (P<0.05). Conclusion: High- and low-frequency rTMS can better improve the cognitive impairment and swallowing function in patients with feeding dysphagia after stroke. |
