| Objective: To compare the Wisconsin Card Sorting Test (WCST) used by patients with Parkinson’s disease in the early and middle stages with traditional cognitive assessment scales, and analyze the characteristics and applicability of cognitive impairment when using WCST for cognitive assessment. Method: A retrospective analysis was conducted on 53 patients with early to middle stage primary Parkinson’s disease who visited our hospital from April 10 to November 15, 2022. They were evaluated with WCST, Mini mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), and Parkinson’s Disease Cognitive Rating Scale (PD-CRS), respectively. The abnormal rate of WCST was compared with the test results of various scales, and the correlation between WCST and the scores of the execution function sub items of each scale was analyzed. Results: A total of 53 patients were included, with H-Y staging ranging from 1 to 3 stages and an average MMSE score of 27.9. A total of 7 patients with scores less than 26 were included, with an abnormality rate of 13.21%; The average score of MoCA was 25.6, with a total of 22 patients scoring less than 26, with an abnormality rate of 41.51%; The average score of PD-CRS was 85.2, with a total of 19 patients with a score less than 80.5, and an abnormality rate of 35.85%. There were a total of 34 patients with abnormal scores in the WCST test, with an abnormality rate of 64.15%. There was a statistically significant difference in the number of patients with cognitive impairment screened by WCST compared to traditional cognitive scales (P<0.01). Correlation analysis showed that WCST scores had varying intensities of correlation with MoCA executive function scores and PD-CRS executive function scores, with cor-relation coefficients ranging from -0.312 to 0.515. Among patients with normal MMSE total score, MoCA total score, and PD-CRS total score, there were 26, 17, and 17 patients with abnormal results in the WCST test, and WCST was also applicable to patients with motor disorders, speech disorders, and decreased vision. Conclusion: WCST is easier to detect the popula-tion of cognitive impairment patients and has a wider applicability in cognitive assessment of Parkinson’s disease patients than MMSE, MoCA, and PD-CRS scales. |
