| Objective: To investigate the efficacy of motor imagery-based brain computer interface (MI-BCI) system for hand function rehabilitation after stroke. Methods: According to the inclusion criteria, 53 chronic stroke patients who were hospitalized，and randomly divided into two groups: the research group (n=25) and the control group (n=28). The research group underwent MI-BCI hand rehabilitation training based on traditional rehabilitation training, while the control group underwent mechanical hand and traditional rehabilitation training. both for 20 times intervention in 4 weeks. The Wolf motor function test (WMFT), Fugl-Meyer assessment for upper extremity (FMA-UE), modified Ashworth score (MAS), 7-level hand function score, grip strength, NIHSS, modified Barthel index (MBI) were used for assessment at baseline, 10 times of intervention, 20 times of intervention, and 1 month of follow-up. Results: After 10 and 20 treatments, and 1-month follow-up, the total WMFT completion time and NIHSS score in both groups reduced compared with the pre-treatment (P<0.05). The total WMFT score, FMA-UE score, FMA-wrist score, research group hand grip strength, and MBI score in both groups increased com-pared with the pre-treatment (P<0.05). The FMA-UE score, FMA-wrist score, hand grip strength, and MBI score in the BG increased compared with the CG (P<0.01), while the NIHSS score in the BG reduced compared with the CG (P<0.05). The 7-level hand function grade in the BG improved compared with the pre-treatment and the CG (P<0.05). There was a sig-nificant time effect (P<0.001) in all indicators between the two groups.And a significant group effect (P<0.05)in the total WMFT completion time and the hand grip strength,which were significantly higher in the BG than in the CG (P<0.05). Conclusion: MI-BCI rehabilitation training system can significantly improve hand function in patients with moderate-to-severe dysfunction in the chronic phase of stroke without significant adverse reactions, and it can be regarded as one of the effective standardized intervention programs. |
