Objective: To study the efficacy of cephalic electroacupuncture therapy for post-stroke cognitive impairment (PSCI) based on magnetic resonance diffusion tensor imaging (DTI). Methods: A total of 64 patients with PSCI were randomly divided into two groups: 32 cases in the experimental group and 32 in the control group. The control group and the treatment group received conventional cognitive function rehabilitation training, and the treatment group was given electroacupuncture therapy additionally. The clinical efficacy of the two groups was compared, and cognitive function as well as the ability to perform activities of daily living was sessed using the Montreal Cognitive Assessment Scale (MoCA), the Mini-Mental State Examination (MMSE), and the Activities of Daily Living (ADL) score. Changes in the white matter fiber bundles of the occipital lobe, frontal lobe, and basal ganglia in PSCI patients were observed using magnetic resonance DTI. The FA values of diffuse fiber bundles in relevant functional areas were correlated with MoCA and MMSE scores using the Pearson test. Results: After treatment, the MoCA, MMSE, and ADL scores in both groups showed significant improvement compared to before treatment, with higher scores in the experimental group. The difference was statistically significant (P<0.05). The FA values of the occipital lobe, frontal lobe, and basal ganglia regions detected by DTI were positively correlated with MoCA (P<0.0001) and MMSE (P<0.0001) in both groups, with a statistically significant difference (P<0.05). The total effective rate of the experimental group was 78.13%, which was significantly higher than that in the control group (65.62%, P<0.05). Conclusion: Cephalic electroacupuncture significantly improves cognitive function and the ability to perform daily living activities in patients with post-stroke cognitive impairment. Based on DTI imaging, the improvement in cognitive function may be related to structural changes in cerebral white matter fiber bundles in the relevant cognitive function areas. |