Objective: To evaluate the effects of threshold respiratory muscle training on the respiratory function and motor function of stroke patients, and explore the optimal training program. Methods: The relevant literatures published in CNKI, Wanfang, VIP, CBM, Cochrane Library, Embase, PubMed and Web of Science were systematically searched before September 2024. The Cochrane bias risk assessment tool and PEDro scale were used to evaluate the quality of the included literature. The RevMan 5.3 was used for data analysis. Results: A total of 16 articles were included, involving 845 patients. The results indicated that TIMT could significantly improve MIP, MEP, FVC, PEF, diaphragmatic thickening rate, diaphragmatic mobility and physical endurance(P<0.01,0.05), but the improvement in FEV1 was not significant . Subgroup analysis of disease duration showed that TIMT performed in the subacute phase was more advantageous for recovery of MEP, FEV1, PEF, and physical endurance. Subgroup analysis of intervention parameters showed that moderate intensity , 20 min/d, 6-12 weeks, and total intervention time of ≤600 min were more effective in improving MIP and had statistically significant differences compared with the control group (P<0.05). 3-4 weeks and total intervention time of ≥720 min were more effective in improving MEP and had statistically significant differences compared with the control group (P<0.05). Conclusion: Compared with conventional treatment or sham stimulation, TIMT significantly improved the respiratory and motor fun-ctions of stroke patients, with the best intervention effects observed within three months after stroke onset. The optimal training regimen is to choose the appropriate training intensity based on the patient’s condition, 20 min per day, 5-6 times per week, for at least 6 weeks. |