Objective: To investigate the clinical rehabilitation effect of end-effector upper limb robot combined with iTBS on upper limb dysfunction in stroke patients. Methods: A total of 60 stroke patients were assigned to a control group and an observation group. Both groups received conventional rehabilitation training. The control group was given iTBS treatment on this basis, while the observation group was given end-effector upper limb robot combined with iTBS. The treatment lasted for 4 weeks. The Fugl-Meyer Assessment of Upper Extremity (FMA-UE), Action Research Arm Test (ARAT), Modified Barthel Index (MBI), amplitude and latency of motor evoked potential (MEP) on the affected hemisphere were compared before and after treatment in both groups. Results: Compared with before treatment, the FMA-UE, ARAT, and MBI scores of both groups after treatment were increased, and the differences were statistically significant (P<0.01). After treatment, the FMA-UE, ARAT, and MBI scores in the observation group were significantly higher than in the control group (P<0.01). After treatment, the amplitude of MEP on the affected hemisphere increased and the latency decreased in both groups as compared with that before treatment (P<0.01), and that in the observation group was significantly greater than in the control group (P<0.01). Conclusion: End-effector upper limb robot combined with iTBS can effectively improve the upper limb motor function and activities of daily living ability of stroke patients, increase the amplitude of MEP, shorten the latency and improve the clinical effect. It is worthy of clinical promotion and application. |