Abstract
Analysis of survival status in stroke patients with severe dysphagia following PEG tube placement
  
DOI:10.3870/zgkf.2025.09.003
EN KeyWords: percutaneous endoscopic gastrostomy  stroke  dysphagia  survival analysis
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作者单位
石青青 中国康复研究中心/北京博爱医院普外科北京 100068 
刘文国 中国康复研究中心/北京博爱医院普外科北京 100068 
徐青 中国康复研究中心/北京博爱医院普外科北京 100068 
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EN Abstract:
  Objective:To investigate factors influencing survival status in stroke patients with severe dysphagia following percutaneous endoscopic gastrostomy (PEG), thereby providing evidence for optimizing clinical management. Methods:This single-center retrospective cohort study was conducted at Beijing Bo’ai Hospital, China Rehabilitation Research Center. The study included 122 patients who underwent initial PEG tube placement between October 2010 and October 2022. Demographic characteristics, stroke type, length of hospitalization, PEG tube retention status, and survival status were collected. Univariate and multivariate logistic regression analyses were performed to evaluate independent predictors of mortality risk. Results:The median follow-up period was 38.5 months (IQR 19.0-57.5). During the follow-up period, 43 patients (35.2%) died and 79 (64.8%) survived. Univariate analysis showed that the deceased patient group was significantly older (P<0.001) and had a significantly shorter median hospital stay (P=0.003) than the surviving group. Complications such as malnutrition, granulation tissue formation, reflux, and pneumonia were significantly more prevalent in deceased patients (all P<0.05). Multivariate logistic regression analysis revealed that ischemic stroke (compared to hemorrhagic stroke) (OR=0.16, 95% CI: 0.05-0.56, P=0.004) and longer hospitalization (OR=0.98, 95% CI: 0.96-0.99, P=0.013) were independent protective factors for survival. Advanced age was an independent risk factor for mortality (OR=1.08, 95% CI: 1.03-1.14, P=0.001). PEG tube removal was associated with significantly higher survival rates than continued retention (OR=175.04, 95% CI: 20.03-1529.38, P<0.001). Conclusion:Stroke type, length of hospitalization, and age are important factors affecting survival in post-PEG patients. Recovery of swallowing function, leading to PEG tube removal, is strongly associated with improved long-term survival, highlighting functional recovery as a key determinant of prognosis.
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