| Objective: To explore the therapeutic efficacy of electroacupuncture and high-energy laser in treating residual pain after minimally invasive surgery for lumbar disc herniation (LDH). Methods: A total of 88 patients with LDH who were hospitalized in our hospital from February 2022 to February 2024 were selected as study participants. They were randomly divided into two groups using the random number table method: the high-energy laser group (n=44) and the electroacupuncture group (n=44). Both groups underwent 4 weeks of routine intervention. Both groups were given routine intervention. The electroacupuncture group received electroacupuncture intervention in addition to the routine intervention, and the high-energy laser group received high-energy laser therapy. The intervention lasted for 4 consecutive weeks. The pain levels, lumbar function improvement, quality of life, inflammatory factors, clinical efficacy, and safety of the two groups were compared before and after the treatment. Results: After 4 weeks of intervention, the VAS scores in the high-energy laser group were significantly lower than those in the electroacupuncture group (P<0.05). After 4 weeks of intervention, both groups showed significant differences compared to before intervention (P<0.05). The JOA lumbar function scores in the high-energy laser group were significantly higher than those in the electroacupuncture group (P<0.05). The SF-36 scores in the high-energy laser group were also significantly higher than those in the electroacupuncture group (P<0.05). The levels of IL-1β, TNF-α, and CRP in the high-energy laser group were significantly lower than those in the electroacupuncture group (P<0.05). Additionally, the overall effective rate of treatment in the high-energy laser group (97.73%) was significantly higher than that in the electroacupuncture group (81.82%) (P<0.05). Conclusion: Compared with elec-troacupuncture intervention, the application of high-energy laser therapy intervention in residual pain after minimally invasive surgery for LDH can promote the improvement of lumbar spine function, reduce serum inflammatory factor levels, thereby improving the clinical efficacy and quality of life of patients, and has high safety. |