Abstract
Research progress on transcranial alternating current stimulation in neurorehabilitation
  
DOI:10.3870/zgkf.2025.10.008
EN KeyWords: transcranial alternating current stimulation  neural oscillations  neurorehabilitation  stroke  Parkinson’s disease
Fund Project:国家重点研发计划项目(2022YFC3602603);北京市石景山区医学重点学科科研项目(2023002)
作者单位
张洪宇 1.首都医科大学附属北京康复医院神经康复中心北京 1001442.首都医科大学北京康复医学院北京 100144 
方伯言 1.首都医科大学附属北京康复医院神经康复中心北京 100144 
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EN Abstract:
  Transcranial alternating current stimulation (tACS) is a novel non-invasive brain stimulation technique that influences neural oscillations and modulates brain network function and plasticity through external rhythmic sine-wave currents. In recent years, research on tACS in neurorehabilitation has increased, showing its potential in motor, sensory, cognitive, and emotional dysfunction. This study systematically reviewed the mechanisms of tACS and its application in neurorehabilitation, and to evaluate its value in diseases such as stroke and Parkinson’s disease. tACS can regulate neural oscillations, promote synaptic plasticity, synchronize brain network activity, and affect neurotransmitters, improving neural function and showing good effects in rehabilitation of various diseases. tACS provides a new approach for neurorehabilitation with broad application prospects. Future studies should optimize individualized parameters and promote clinical translation.
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