| Transcranial alternating current stimulation (tACS) is a novel non-invasive brain stimulation technique that influences neural oscillations and modulates brain network function and plasticity through external rhythmic sine-wave currents. In recent years, research on tACS in neurorehabilitation has increased, showing its potential in motor, sensory, cognitive, and emotional dysfunction. This study systematically reviewed the mechanisms of tACS and its application in neurorehabilitation, and to evaluate its value in diseases such as stroke and Parkinson’s disease. tACS can regulate neural oscillations, promote synaptic plasticity, synchronize brain network activity, and affect neurotransmitters, improving neural function and showing good effects in rehabilitation of various diseases. tACS provides a new approach for neurorehabilitation with broad application prospects. Future studies should optimize individualized parameters and promote clinical translation. |