Abstract
Applications of functional near-infrared spectroscopy (fNIRS) neuroimaging in stroke rehabilitation: a review
  
DOI:10.3870/zgkf.2025.10.009
EN KeyWords: functional near-infrared spectroscopy  stroke  rehabilitation  neural plasticity
Fund Project:浙江省中医药科技计划项目(2024ZL593,2024ZL1254)
作者单位
张璐 1.浙江大学医学院附属邵逸夫医院康复医学科杭州 310000 
杨可桢 1.浙江大学医学院附属邵逸夫医院康复医学科杭州 310000 
廖志平 1.浙江大学医学院附属邵逸夫医院康复医学科杭州 310000 
宋海新 1.浙江大学医学院附属邵逸夫医院康复医学科杭州 310000 
杨丛慧 2.温岭市第一人民医院康复医学科浙江 台州 317500 
李建华 1.浙江大学医学院附属邵逸夫医院康复医学科杭州 310000 
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EN Abstract:
  Early diagnosis and rehabilitation assessment of functional disorders after stroke remain a clinical challenge. Traditional neuroimaging techniques are limited by their temporal and spatial resolution. Functional near-infrared spectroscopy (fNIRS) offers a non-invasive, high temporal resolution, and motion-tolerant approach, providing a new means to explore the mechanisms of stroke rehabilitation. A systematic search was conducted in PubMed, Web of Science, and CNKI databases from Janury 2000 to December 2023, using keywords such as “fNIRS”, “stroke rehabilitation”, and “neural plasticity”. Clinical studies and mechanism exploration articles were included, excluding those involving non-stroke populations. The studies confirmed that: fNIRS can dynamically capture the evolution of cortical activation patterns after stroke, revealing neural remodeling features such as contralateral compensation and bilateral balance recovery. It shows high sensitivity in the evaluation of robot-assisted training and rTMS efficacy. Neurofeedback technology significantly enhances the effect of motor imagery training. However, it still has limitations such as limited spatial resolution, susceptibility to physiological noise, and the lack of standardized data analysis procedures. fNIRS promotes the development of individualized rehabilitation strategies through real-time brain function monitoring. In the future, it is necessary to establish unified clinical application standards through multimodal fusion, algorithm optimization, and large-sample studies.
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