| Objective: To explore the clinical efficacy of pursed-lip abdominal breathing training combined with high-flow nasal cannula oxygen therapy (HFNC), breathing trainer and diaphragm pacing in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods: A total of 150 patients with AECOPD were divided into general group (drug therapy alone), control group (drug therapy+pursed-lip abdominal breathing training), observation group 1 (drug therapy+pursed-lip abdominal breathing training+HFNC), observation group 2 (drug therapy+pursed-lip abdominal breathing training+breathing trainer) and observation group 3 (drug therapy+pursed-lip-abdominal breathing training+diaphragm pacing) according to random number table method, with 30 cases in each group. Pulmonary function indexes, arterial blood gas indexes, 6-min walking test (6-MWT) results and health status of each group were compared. Results: After 2 weeks of treatment, the first second forced end-expiratory volume (FEV1), forced vital capacity (FVC), FEV1/FVC，partial pressure of oxygen (PaO2), arterial oxygen saturation (SaO2) and 6-MWT walking distance of all groups were increased. Residual volume/total lung volume, partial pressure of carbon dioxide (PaCO2), COPD assessment test (CAT) and modified Medical Research Council Dyspnea Scale (mMRC) scores were all decreased, and the indexes of observation groups (1, 2, 3) were increased and decreased more significantly than those of control group and general group (P<0.05). The increase and decrease of all indexes in the control group were more obvious than those in the general group (P<0.05), and there was no statistically significant difference among the observation groups (1, 2, 3). Conclusion: pursed-lip breathing training combined with HFNC, breathing trainer and diaphragm pacing has good application effects in AECOPD patients, which can effectively improve the lung function and blood gas analysis indexes of patients, increase the walking distance of pa-tients, and optimize the health status of patients. |
