| Objective: To develop a non-pharmacological prevention guideline for cognitive impairment in the elderly in China and provide guidance for the prevention of cognitive impairment in the elderly population in China. Methods: Initiated by the project team of the National Key Research and Development Program of China (2022YFC3601204, 2022YFC3601200), an expert team of rehabilitation medicine and neuroscience was established. Through several rounds of meetings, combined with evidence-based medical methodology, clinical research data were systematically retrieved and evidence quality was evaluated to formulate the content of the guidelines. Results: This guideline systematically reviews and evaluates evidence regarding risk factors for cognitive impairment in older adults and the effectiveness of non-pharmacological preventive measures, including cognitive training, physical exercise, and healthy lifestyle interventions. To better promote early identification and intervention of cognitive impairment in older adults, the guideline provides evidence-based recommendations with graded levels of confidence for early detection strategies, including non-invasive neuromodulation technologies for early intervention. Tailored to national conditions, the guideline also offers practical recommendations for care support systems tailored to elderly cognitive impairment management. Conclusion: This guideline provides evidence of the effectiveness of multi-level and multidisciplinary assistance for the risk factors, non-pharmacological prevention, early identification and early intervention of cognitive impairment in the elderly, and provides guidance for promoting the research and practice of cognitive impairment prevention and treatment in the elderly population in China. |
