| Lower limb motor dysfunction caused by various neurological diseases often severely impacts patients’ quality of daily life. Repetitive transcranial magnetic stimulation (rTMS) can ameliorate motor impairments resulting from neural damage by modulating neural excitability. Among the stimulation targets, the cerebellum has garnered increasing attention due to its crucial role in balance function. However, the stimulation protocols used in current studies are not yet standardized, and the therapeutic efficacy remains uncertain. Therefore, this review summarizes research on cerebellar rTMS in various neurological disorders. The findings indicate that cerebellar rTMS demonstrates varying degrees of clinical effectiveness in stroke, spinocerebellar ataxia, Parkinson’s disease, and other neurological conditions. It primarily improves lower limb motor dysfunction by enhancing cerebellar blood flow and metabolism, as well as modulating the cerebellar-thalamo-cortical circuit. This provides additional references and a theoretical basis for the clinical application of cerebellar rTMS. |
