| Objective：To explore the impact of median nerve stimulation (MNS) combined with the γ-rhythmic oscillations generated by 40 Hz auditory stimulation on the consciousness state of patients with acquired brain injury. Methods：A total of 72 patients with consciousness disorders following acquired brain injury were divided into a control group, an MNS group, and an observation group using a random number table method, with 24 patients in each group. The control group received conventional rehabilitation intervention, while the MNS group received MNS in addition to the treatment in the control group. The observation group received stimulation with a single tone at a constant frequency of 40 Hz and an amplitude of 0.8 Pa, based on the MNS group's treatment. Before and after 4 weeks of treatment, the Glasgow Coma Scale (GCS), Coma Recovery Scale-Revised (CRS-R), Full Unresponsiveness Outcome Rating Scale (FOUR), and event-related potential (ERP) were used to assess the consciousness state of the patients. Results: After treatment, the GCS, CRS-R, FOUR scores, and MMN amplitude and P300 amplitude indicators in all three groups increased compared to those before treatment, while the MMN latency decreased compared to that before treatment (P<0.05). Intergroup comparisons revealed that the GCS, CRS-R, FOUR scores, and MMN amplitude and P300 amplitude in the observation group and MNS group were higher than those in the control group, and the MMN latency was lower than that in the control group (P<0.05). Furthermore, the above indicators in the observation group were superior to those in the MNS group (P<0.05). Conclusion: The treatment of γ-rhythmic oscillations generated by median nerve electrical stimulation combined with 40 Hz auditory stimulation can significantly improve the consciousness state and level of patients with acquired brain injuries. |
