| Objective：To explore the clinical efficacy of transcranial magnetic stimulation combined with patch technique in the treatment of motor dysfunction in ischemic stroke. Methods：Totally, 120 patients with ischemic stroke accompanied by motor dysfunction who received treatment in the Rehabilitation Department of Xingtai People’s Hospital from June 2024 to June 2025 were selected. The patients were randomly divided into four groups using a random number table method, with 30 patients in each group: group A (general treatment group), group B (patch group), group C (transcranial magnetic stimulation group), and group D (transcranial magnetic stimulation + patch group). The Fugl-Meyer Assessment (FMA) scores, Barthel Index (BI) scores, National Institutes of Health Stroke Scale (NIHSS) scores, manual muscle test (MMT) scores, maximum systolic blood flow velocity (Vs), end diastolic blood flow velocity (Vd), vascular resistance index (RI), and serum levels of soluble intercellular adhesion molecule-1 (sICAM-1), high sensitivity C-reactive protein (hs-CRP) and interleukin-6 (IL-6) before and after treatment in each group were compared. Results：After treatment, the FMA, BI, elbow flexion muscle group, and forearm pronator muscle group scores of patients in groups B, C, and D were significantly higher than those in group A (P<0.05), and the NIHSS score was lower than that in group A (P<0.05). The FMA, BI, elbow flexion muscle group, and forearm pronator muscle group scores of patients in group D were significantly higher than those in groups B and C (P<0.05), and the NIHSS score was lower than that in groups B and C (P<0.05). There was no statistically significant difference in the scores of FMA, BI, NIHSS, elbow flexion muscle group, and forearm pronator muscle group between group B and group C. After the treatment, the RI of patients in groups B, C, and D was significantly lower than that in group A (P<0.05), and the Vs and Vd were significantly higher than those in group A (P<0.05). The RI of patients in group D was significantly lower than that in groups B and C (P<0.05), and the Vs and Vd were significantly higher than those in groups B and C (P<0.05). There was no statistically significant difference in RI, Vs, and Vd between groups B and C. After the treatment, the average serum levels of sICAM-1, Hs-CRP, and IL-6 in groups B, C, and D were significantly lower than those in group A (P<0.05), and those in group D were significantly lower than those in groups B and C (P<0.05). There was no statistically significant difference in the levels of sICAM-1, Hs-CRP, and IL-6 between groups B and C. Conclusion：The application of transcranial magnetic stimulation combined with patch technique has shown satisfactory results in patients with ischemic stroke, which can improve their limb motor function and muscle strength, enhance their daily living ability, improve cerebral hemodynamics, reduce inflammatory reactions, and promote neurological function recovery. |
