| 陈建敏,张楠楠,王志勇.运动训练对肝硬化患者运动功能的疗效观察[J].中国康复,2019,34(1):30-33 |
| 运动训练对肝硬化患者运动功能的疗效观察 |
| Effects of an exercise program in patients with hepatic cirrhosis |
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| DOI： |
| 中文关键词: 肝硬化 运动训练 运动功能 健康相关生活质量 |
| 英文关键词: hepatic cirrhosis exercise program exercise capacity health related quality of life |
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| 中文摘要: |
| 目的：观察运动训练对肝硬化患者运动功能的影响。方法：将20例肝硬化患者随机分为运动组和常规组各10例，均接受常规药物治疗，运动组在此基础上给予8周的适度运动训练。分别在治疗前后采用超声下股四头肌的厚度评估肌肉质量，等速肌力测试评估伸膝肌力，6min步行距离（6MWD）评估运动能力，同时采用慢性肝病调查问卷（CLDQ）评估健康相关生活质量（HRQoL），监测运动前后肝硬化严重程度及血液指标变化。结果：干预后运动组患者的6MWD、股四头肌的厚度、伸膝肌力、CLDQ评估中乏力、活动2项评分较治疗前及常规组比较均有显著提高（P<0.05）。结论：适度的运动训练可提高肝硬化患者的运动功能，提高健康相关生活质量。 |
| 英文摘要: |
| Objective: To observe the effect of an exercise program in patients with hepatic cirrhosis. Methods: Twenty patients with hepatic cirrhosis were randomly divided into exercise group and control group, n=10 in each group. The control group and exercise group were treated with routine medical management. The exercise group were additionally given the program of moderate exercise for 8 weeks under supervision of a physiotherapist. Before and after the 8 week intervention, we determined exercise capacity (6 minute walk distance, 6MWD), quadriceps muscle thickness (measured by ultrasound), isometric knee extension (isometric dynamometer), and health related quality of life (HRQoL) by answers from Chronic Liver Disease Questionnaires (CLDQ). Results： After intervention, 6MWD, quadriceps muscle thickness, isometric knee extension, and scores of fatigue and activity in CLDQ were significantly increased in exercise group as compared with those before intervention and in control group (P<0.05 for all). Conclusion: Physical exercise could improve exercise capacity, muscle mass, and HRQoL in patients with hepatic cirrhosis. |
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