Objective: To explore the changes of autonomic nervous function by depressurization in primary hypertension patients. Methods: All 106 cases of primary hypertension were randomly divided into three groups: the resistance group (35 cases), aerobic group (36 cases) and combination group (35 cases). All three groups accepted oral administration of drugs. The resistance group accepted moderate intensity resistance exercise, the aerobic group accepted jogging, and combination group accepted aerobic resistance movement additionally. After the treatment course, the hemodynamic indexes and cardiovascular autonomic nerve functions in three groups were evaluated. Results: After the treatment, systolic and diastolic blood pressure in all three groups were significantly lower than those before treatment (all P<0.05). Systolic and diastolic blood pressure in combination group was relatively lower than in resistance and aerobic groups (all P<0.05). The heart rate variability (HRV)-high frequency (HF) in resistance group was significantly lower than that pretreatment, and HRV-low frequency (LF) and HRV power-LF/HF were significantly higher than pretreatment. HRV-HF in aerobic group and combination group were significantly higher and HRV-LF and HRV-LF/HF were significantly lower than those pretreatment (all P<0.05). After treatment, HRV-HF was the highest and HRV-LF and HRV-LF/HF lowest in combination group, followed in aerobic group (all P<0.05); BPV-LF in aerobic group and combination group were significantly lower than pretreatment, and BPV-LF in resistance group was higher than pretreatment (all P<0.05). There were no significant differences among three groups (P>0.05). BPV-LF was lowest in combination group, followed in aerobic group, and lowest in resistance group (all P<0.05). Conclusion: Aerobic resistance exercise can significantly improve autonomic nervous system in patients with primary hypertension, and is superior to resistance or aerobic exercise alone. |